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11 Aug 2010
by Working Group

Posted in Front Lines of TB R&D

This week in TB R&D – 10 August 2010

This week we reposted an article from DailyFinance.com regarding a new antibactierial compound from GlaxoSmithKline (GSK). GSK has recently published a Nature paper describing the 2.1 angstom crystal structure of Staphylococcus aureus DNA gyrase (a Type IIA topoisomerase) and DNA in complex with their new broad-spectrum antibacterial compound (GSK299423).

25 Mar 2010
by Khisi Mdluli

Posted in Front Lines of TB R&D

Impact of the CPTR Initiative

After a decades-long drought, new pharmaceutical discoveries and repurposing of existing antimicrobials have produced about 10 drugs from 7 different classes which are now in various stages of clinical development for TB.

18 Mar 2010
by Working Group

Posted in Front Lines of TB R&D, TB News

Launch of the Critical Path to TB Drug Regimens

Today marks the launch of an exciting new initiative in TB R&D. The US Food and Drug Administration (FDA) has supported the Critical Path to TB Drug Regimens (CPTR). The CPTR comprises a broad collaborative network of partners including pharmaceutical companies, government, academia, and advocates, and NGOs with the focus to accelerate the development of new, safe, and highly effective shorter length TB treatment regimens.